Biomarker Glossary
Understand the biomarkers that GATOR tracks. Learn what each marker measures, optimal reference ranges, and how they relate to your health.
ApoB (Apolipoprotein B)
CardiovascularIn-Depth GuidePrimary marker for atherogenic particle count and cardiovascular risk.
HbA1c (Glycated Hemoglobin)
MetabolicIn-Depth GuideAverage blood sugar levels over the past 2β3 months.
Testosterone
HormoneIn-Depth GuidePrimary androgen hormone affecting muscle, energy, mood, and metabolism.
DHEA-S (Dehydroepiandrosterone Sulfate)
HormoneIn-Depth GuideAdrenal hormone precursor linked to aging, vitality, and immune function.
Vitamin D (25-Hydroxyvitamin D)
InflammationIn-Depth GuideEssential for bone health, immune function, and inflammation regulation.
Ferritin
IronIn-Depth GuideIron storage protein indicating total body iron reserves.
TSH (Thyroid Stimulating Hormone)
ThyroidIn-Depth GuideMaster regulator of thyroid function and metabolic rate.
Free T3 (Triiodothyronine)
ThyroidIn-Depth GuideThe active thyroid hormone driving cellular metabolism.
Free T4 (Thyroxine)
ThyroidIn-Depth GuidePrimary thyroid hormone output, converted to active T3 in tissues.
hsCRP (High-Sensitivity C-Reactive Protein)
InflammationIn-Depth GuideSensitive marker for systemic inflammation and cardiovascular risk.
Homocysteine
CardiovascularIn-Depth GuideAmino acid linked to cardiovascular risk and methylation status.
LDL Cholesterol
CardiovascularIn-Depth GuideLow-density lipoprotein cholesterol, a key cardiovascular risk factor.
HDL Cholesterol
CardiovascularIn-Depth GuideHigh-density lipoprotein cholesterol supporting reverse cholesterol transport.
Triglycerides
CardiovascularIn-Depth GuideBlood fats linked to metabolic health, insulin resistance, and heart disease.
Fasting Insulin
MetabolicIn-Depth GuideEarly indicator of insulin resistance, often elevated before blood sugar rises.
Fasting Glucose
MetabolicIn-Depth GuideBlood sugar after fasting, used to screen for diabetes and metabolic health.
ALT (Alanine Aminotransferase)
LiverLiver enzyme that rises with liver cell damage or inflammation.
AST (Aspartate Aminotransferase)
LiverEnzyme found in liver, heart, and muscle; rises with tissue damage.
Cortisol
HormoneIn-Depth GuidePrimary stress hormone regulating metabolism, immunity, and inflammation.
SHBG (Sex Hormone-Binding Globulin)
HormoneProtein that binds testosterone and estrogen, regulating hormone availability.
Lipoprotein(a)
CardiovascularIn-Depth GuideGenetic cardiovascular risk marker independent of LDL.
Apolipoprotein A1
CardiovascularPrimary protein in HDL β protective against atherosclerosis.
Non-HDL Cholesterol
CardiovascularAll atherogenic cholesterol combined β better predictor than LDL alone.
C-Peptide
MetabolicDirect measure of insulin production by the pancreas.
Uric Acid
MetabolicByproduct of purine metabolism β elevated levels linked to gout and cardiovascular disease.
IGF-1 (Insulin-like Growth Factor 1)
MetabolicGrowth hormone mediator β reflects HGH status and anabolic capacity.
Reverse T3 (rT3)
ThyroidInactive thyroid metabolite that blocks T3 receptors under stress.
TPO Antibodies
ThyroidAutoimmune marker for Hashimoto's thyroiditis.
GGT (Gamma-Glutamyl Transferase)
LiverLiver enzyme sensitive to alcohol use and bile duct function.
ALP (Alkaline Phosphatase)
LiverEnzyme from liver, bone, and intestines β helps evaluate bile duct and bone health.
Cystatin C
KidneyMore accurate kidney function marker than creatinine alone.
BUN (Blood Urea Nitrogen)
KidneyWaste product from protein metabolism filtered by kidneys.
Creatinine
KidneyMuscle metabolism byproduct used to estimate kidney filtration rate.
Fibrinogen
InflammationClotting protein and acute-phase inflammatory marker.
Estradiol (E2)
HormonePrimary estrogen β critical for bone, cardiovascular, and brain health.
Progesterone
HormoneEssential for menstrual cycle regulation, pregnancy, and sleep.
Prolactin
HormonePituitary hormone β elevated levels may indicate pituitary issues.
Free Testosterone
HormoneBioavailable testosterone β the fraction that actively binds to receptors.
Vitamin B12 (Cobalamin)
VitaminsIn-Depth GuideEssential for nerve function, DNA synthesis, and red blood cell formation.
Selenium
VitaminsTrace mineral essential for thyroid function and antioxidant defense.
Zinc
VitaminsEssential mineral for immune function, testosterone, and wound healing.
Copper
VitaminsTrace mineral for iron metabolism, connective tissue, and brain function.
RDW (Red Cell Distribution Width)
BloodMeasures variation in red blood cell size β elevated levels signal nutritional deficiency.
MPV (Mean Platelet Volume)
BloodAverage platelet size β larger platelets are more reactive.
NT-proBNP
CardiacGold-standard biomarker for heart failure screening and monitoring.
FSH (Follicle-Stimulating Hormone)
HormoneKey reproductive hormone β levels vary dramatically by cycle phase and menopausal status.
LH (Luteinizing Hormone)
HormoneTriggers ovulation β the mid-cycle LH surge is the key fertility signal.
Progesterone
HormonePrimary luteal phase hormone β confirms ovulation and supports early pregnancy.
AMH (Anti-MΓΌllerian Hormone)
HormoneBest marker of ovarian reserve β does NOT vary by cycle phase.
Prolactin
HormonePituitary hormone β elevated levels can disrupt menstrual cycles and fertility.
SHBG (Sex Hormone Binding Globulin)
HormoneCarrier protein that determines how much testosterone and estrogen is biologically active.
Albumin
LiverPrimary protein made by the liver β reflects nutritional status and liver function.
Globulin
LiverImmune and transport proteins β elevated levels may signal chronic inflammation or infection.
Total Protein
LiverSum of albumin and globulin β screens for liver, kidney, and nutritional disorders.
Calcium
MetabolicEssential mineral for bones, muscles, and nerve signaling β tightly regulated by parathyroid.
Phosphorus
MetabolicWorks with calcium for bone health β also critical for energy production (ATP).
Magnesium
MetabolicInvolved in 300+ enzymatic reactions β deficiency is common and underdiagnosed.
Sodium
MetabolicPrimary electrolyte regulating fluid balance and blood pressure.
Potassium
MetabolicCritical electrolyte for heart rhythm and muscle function β both high and low are dangerous.
Chloride
MetabolicElectrolyte maintaining acid-base balance β usually moves with sodium.
Carbon Dioxide (CO2/Bicarbonate)
MetabolicReflects acid-base status β part of the metabolic panel.
eGFR (Estimated Glomerular Filtration Rate)
KidneyBest single test for kidney function β estimates how well kidneys filter blood.
Direct Bilirubin (Conjugated)
LiverProcessed form of bilirubin β elevated levels suggest bile duct obstruction.
Platelet Count
BloodBlood clotting cells β both high and low counts carry clinical significance.
RBC Count (Red Blood Cells)
BloodNumber of red blood cells β carries oxygen throughout the body.
WBC Count (White Blood Cells)
BloodTotal white blood cell count β first-line immune status indicator.
Total Bilirubin
LiverPigment from red blood cell breakdown β mildly elevated levels may be protective (Gilbert syndrome).
Serum Iron
IronCirculating iron in the blood β fluctuates throughout the day and with meals.
TIBC (Total Iron Binding Capacity)
IronMeasures the blood's capacity to transport iron β rises when iron stores are low.
Transferrin Saturation
IronPercentage of iron-carrying proteins that are loaded with iron β key for detecting overload and deficiency.
Folate (Vitamin B9)
MetabolicEssential B vitamin for DNA synthesis, methylation, and neural tube development.
Vitamin A (Retinol)
MetabolicFat-soluble vitamin essential for vision, immune function, and skin health.
Vitamin B6 (Pyridoxine)
MetabolicCoenzyme in over 100 reactions β critical for neurotransmitter synthesis and homocysteine metabolism.
Vitamin E (Alpha-Tocopherol)
MetabolicFat-soluble antioxidant protecting cell membranes from oxidative damage.
Vitamin C (Ascorbic Acid)
MetabolicWater-soluble antioxidant critical for collagen synthesis, immune defense, and iron absorption.
ESR (Erythrocyte Sedimentation Rate)
InflammationNon-specific inflammation marker β measures how fast red blood cells settle.
MCV (Mean Corpuscular Volume)
BloodAverage red blood cell size β helps classify the type of anemia.
MCH (Mean Corpuscular Hemoglobin)
BloodAverage hemoglobin content per red blood cell β parallels MCV in anemia classification.
MCHC (Mean Corpuscular Hemoglobin Concentration)
BloodHemoglobin concentration within red blood cells β reflects iron loading per cell.
Hemoglobin
BloodOxygen-carrying protein in red blood cells β the primary marker for anemia.
Hematocrit
BloodPercentage of blood volume occupied by red blood cells β reflects hydration and oxygen capacity.
Neutrophils
BloodMost abundant white blood cell β first responders to bacterial infection.
Lymphocytes
BloodAdaptive immune cells (T cells, B cells, NK cells) β rise with viral infections.
Total Cholesterol
CardiovascularSum of all cholesterol fractions β useful as a screening tool but limited on its own.
VLDL Cholesterol
CardiovascularTriglyceride-rich lipoprotein β elevated levels reflect metabolic dysfunction.
Omega-3 Index
CardiovascularPercentage of EPA+DHA in red blood cell membranes β strong predictor of cardiac risk.
Lp-PLA2 (Lipoprotein-Associated Phospholipase A2)
CardiovascularVascular-specific inflammation marker β more specific to atherosclerosis than hsCRP.
Troponin (High-Sensitivity)
CardiacGold-standard marker for heart muscle damage β detects even minor myocardial injury.
Growth Hormone (GH/HGH)
HormonePituitary hormone driving growth, repair, and metabolism β pulsatile and difficult to measure.
Adiponectin
MetabolicAnti-inflammatory hormone from fat cells β higher levels indicate better metabolic health.
Leptin
MetabolicSatiety hormone from fat cells β elevated levels indicate leptin resistance, not protection.