Progesterone
Progesterone is produced by the ovaries after ovulation and by the adrenal glands. It prepares the uterine lining for implantation and supports pregnancy. Progesterone also promotes calm, sleep, and GABA activity.
Low progesterone relative to estrogen (estrogen dominance) can cause PMS, anxiety, and irregular cycles.
What It Measures
Serum progesterone levels, ideally tested mid-luteal phase (day 19–22).
Reference Ranges
| Status | Range (ng/mL) |
|---|---|
| Optimal | Luteal phase: 10–25 ng/mL |
| Normal | Phase-dependent |
| Borderline | Luteal < 5 ng/mL |
| Out of Range | Anovulatory: < 1 ng/mL |
Range by Cycle Phase
| Cycle Phase | Reference Range |
|---|---|
| Follicular | < 1 ng/mL (days 1–13) |
| Ovulatory | 2–25 ng/mL (around ovulation) |
| Luteal | 5–20 ng/mL (days 17–28, peak 7 DPO) |
| Menopause | < 1 ng/mL |
Source: Endocrine Society, ACOG. Ranges are approximate — consult your provider.
When to test: Day 21 (or 7 days post-ovulation) for confirmation of ovulation.
Interpreting Your Results
When Values Are High
Confirms ovulation occurred. Very high may indicate molar pregnancy or congenital adrenal hyperplasia.
When Values Are Low
Anovulation, luteal phase defect, or impending miscarriage. Symptoms: irregular cycles, PMS, anxiety, insomnia.
How GATOR Tracks This
Lab Providers
Related Biomarkers
This content is for informational purposes only and does not constitute medical advice. Reference ranges may vary by laboratory and individual factors. Consult a qualified healthcare provider for interpretation of your results and treatment decisions.
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