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Cardiovascular

Omega-3 Index

The Omega-3 Index measures the percentage of EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) in red blood cell membranes. It reflects long-term omega-3 status over approximately 120 days (the lifespan of a red blood cell), similar to how HbA1c reflects average glucose.

An Omega-3 Index of 8–12% is associated with the lowest cardiovascular risk, while < 4% is considered high risk. The index has been validated as an independent predictor of sudden cardiac death and correlates with reduced inflammation, improved endothelial function, and lower triglycerides.

The Omega-3 Index is primarily influenced by dietary intake of fatty fish and omega-3 supplements (fish oil, algae oil). It is not significantly affected by short-term dietary changes.

What It Measures

Percentage of EPA and DHA as a proportion of total fatty acids in red blood cell membranes.

Reference Ranges

StatusRange (%)
Optimal8–12%
Normal4–8%
Borderline4% (high risk zone)
Out of Range< 4% (highest cardiac risk)

How GATOR Tracks This

Lab Providers

Function HealthLabCorp

Related Biomarkers

This content is for informational purposes only and does not constitute medical advice. Reference ranges may vary by laboratory and individual factors. Consult a qualified healthcare provider for interpretation of your results and treatment decisions.

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