Total Bilirubin
Total bilirubin measures both direct (conjugated) and indirect (unconjugated) bilirubin in the blood. Bilirubin is produced when the liver breaks down old red blood cells. It is processed (conjugated) by the liver and excreted in bile.
Mild elevations (1.0–3.0 mg/dL) are often benign and may indicate Gilbert syndrome, a common genetic variant affecting 3–7% of the population. Research suggests mildly elevated bilirubin has antioxidant properties and may be cardioprotective.
Significantly elevated bilirubin causes jaundice (yellowing of the skin and eyes) and can indicate liver disease, bile duct obstruction, or hemolytic anemia.
What It Measures
Total concentration of bilirubin (direct + indirect) in blood serum, reflecting red blood cell turnover and liver processing capacity.
Reference Ranges
| Status | Range (mg/dL) |
|---|---|
| Optimal | 0.3–1.0 mg/dL |
| Normal | 0.1–1.2 mg/dL |
| Borderline | 1.2–2.0 mg/dL |
| Out of Range | > 2.0 mg/dL |
How GATOR Tracks This
Lab Providers
Related Biomarkers
This content is for informational purposes only and does not constitute medical advice. Reference ranges may vary by laboratory and individual factors. Consult a qualified healthcare provider for interpretation of your results and treatment decisions.
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