Troponin (High-Sensitivity)
High-sensitivity troponin (hs-TnI or hs-TnT) measures tiny amounts of troponin protein released when heart muscle cells are damaged. It is the definitive biomarker for diagnosing acute myocardial infarction (heart attack).
High-sensitivity assays can detect troponin levels 10–100x lower than conventional tests, enabling earlier diagnosis and detection of subclinical myocardial injury. Chronically elevated troponin (even at very low levels) is associated with increased long-term cardiovascular risk and mortality.
Important: troponin elevation is not always a heart attack. Other causes include myocarditis, heart failure, pulmonary embolism, sepsis, renal failure, and extreme endurance exercise. Clinical context and serial measurements are essential for interpretation.
What It Measures
Cardiac troponin protein released from damaged heart muscle cells, detected at very low concentrations by high-sensitivity assays.
Reference Ranges
| Status | Range (ng/L) |
|---|---|
| Optimal | < 14 ng/L (hs-TnT) |
| Normal | < 14 ng/L (99th percentile) |
| Borderline | 14–52 ng/L (observe serial change) |
| Out of Range | > 52 ng/L (significant myocardial injury) |
How GATOR Tracks This
Lab Providers
Related Biomarkers
This content is for informational purposes only and does not constitute medical advice. Reference ranges may vary by laboratory and individual factors. Consult a qualified healthcare provider for interpretation of your results and treatment decisions.
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