Serum Iron
Serum iron measures the amount of circulating iron bound to transferrin in the blood. Iron is essential for oxygen transport (hemoglobin), energy production, and immune function.
Serum iron is a volatile marker — it varies significantly with time of day (highest in the morning), recent meals (especially iron-rich foods), and inflammation. For this reason, it should always be interpreted alongside ferritin, TIBC, and transferrin saturation for a complete picture of iron status.
Low serum iron can indicate iron deficiency, chronic disease, or poor absorption. High serum iron may suggest iron overload (hemochromatosis), liver damage, or excessive supplementation.
What It Measures
Concentration of iron bound to transferrin protein in blood serum at the time of the draw.
Reference Ranges
| Status | Range (mcg/dL) |
|---|---|
| Optimal | 60–170 mcg/dL |
| Normal | 50–170 mcg/dL (men), 40–150 mcg/dL (women) |
| Borderline | 30–50 mcg/dL |
| Out of Range | < 30 mcg/dL or > 200 mcg/dL |
How GATOR Tracks This
Lab Providers
Related Clinical Ratios
Related Biomarkers
This content is for informational purposes only and does not constitute medical advice. Reference ranges may vary by laboratory and individual factors. Consult a qualified healthcare provider for interpretation of your results and treatment decisions.
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