Sodium/Potassium Ratio
Formula
Na / KWhat It Reveals
Electrolyte balance, adrenal function, and cardiovascular risk.
Interpretation Ranges
Optimal
28–34
Healthy electrolyte balance
Borderline
25–28 or 34–38
Mild imbalance — assess diet and adrenal function
High Risk
< 25 or > 38
Significant electrolyte dysregulation — evaluate adrenal and renal function
Clinical Significance
The Na/K ratio reflects the interplay between dietary sodium, potassium intake, aldosterone activity, and renal regulation. WHO recommends a urinary Na/K ratio below 1.0 (molar) for cardiovascular protection. Serum ratios outside 28–34 may indicate adrenal insufficiency, Cushing syndrome, or renal tubular dysfunction.
What To Do
If high (excess sodium relative to potassium): increase potassium-rich foods (bananas, leafy greens, avocados), reduce sodium. If low: evaluate for Addison disease or aldosterone deficiency. Check adrenal function with cortisol and ACTH if persistently abnormal.
Component Biomarkers
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Source: BMJ 2016; WHO Sodium/Potassium Intake Guidelines
This content is for informational purposes only and does not constitute medical advice. Consult a qualified healthcare provider for interpretation of your results.