HOMA-IR
Formula
(Glucose × Insulin) / 405What It Reveals
Insulin resistance — how well your cells respond to insulin.
Interpretation Ranges
Optimal
< 1.0
Excellent insulin sensitivity
Borderline
1.0–2.0
Early insulin resistance — lifestyle intervention recommended
High Risk
> 2.0
Significant insulin resistance — metabolic syndrome risk
Clinical Significance
HOMA-IR is the gold standard for estimating insulin resistance without an oral glucose tolerance test. It predicts Type 2 diabetes development 5–10 years before HbA1c rises.
What To Do
Prioritize resistance training and Zone 2 cardio. Reduce refined carbohydrates. Time-restricted eating may help. Monitor with CGM.
Component Biomarkers
GATOR Calculates This Automatically
Upload your lab results and GATOR calculates HOMA-IR along with 16 other clinical ratios — tracked over time with AI-powered insights.
Source: Diabetes Care 2000, Matthews et al.
This content is for informational purposes only and does not constitute medical advice. Consult a qualified healthcare provider for interpretation of your results.